Single-dose azithromycin microsphere formulation: a novel delivery system for antibiotics

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Single-dose azithromycin microsphere formulation: a novel delivery system for antibiotics

Azithromycin extended release (Zmax, Pfizer Inc) is a novel single-dose administration formulation of azithromycin which won FDA approval in June 2005 and is currently approved for the treatment of community acquired pneumonia and acute bacterial sinusitis. Azitromycin is incorporated into sustained-release microspheres which release the drug slowly through 200 microm pores. Because of this sus...

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A Review on Microsphere for Novel Drug Delivery System

The Non ideal pharmaceutical, pharmacokinetic, and therapeutic properties often combine to reduce the effectiveness of certain compounds. For the vectoring of such compounds to target areas, liposomes, nanoparticles, and microspheres have been suggested. The range of techniques for the preparation of microspheres offers a variety of opportunities to control aspects of drug administration. This ...

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ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2007

ISSN: 1176-9114

DOI: 10.2147/nano.2007.2.1.9